Effects of Vitamin C, Quercetin, Bromelain, Licorice, Zinc, Piperine, and Nattokinase on Long Post-COVID Vaccination Syndrome (LPCVS) & Long Haul

Introduction

These supplements and natural compounds have shown potential benefits in managing viral infections, inflammation, and immune responses, which can be relevant for conditions like Long Haul COVID, LPCVS, and viral reactivations. Here’s a detailed look at their effects:

Vitamin C

Effects

Antioxidant: Reduces oxidative stress and inflammation.

Immune Support: Enhances the function of various immune cells and supports the body’s antiviral defences.

Relevant Conditions

LC & LPCVS: May help reduce inflammation and support immune function.

Viral Infections: Shown to reduce symptoms and duration of viral infections including those caused by EBV, CMV, and HHV-6.

Sources

• Journal of Clinical Medicine
• Nutrients

Quercetin

Effects

Anti-inflammatory and Antioxidant: Modulates inflammatory pathways and oxidative stress.

Antiviral: Inhibits replication of several viruses, including coronaviruses and herpesviruses.

Relevant Conditions

LC & LPCVS: Reduces inflammation and oxidative stress.

Viral Infections: Shown to have antiviral activity against EBV, CMV, and others.

Sources

• Viruses
• Nutrients

Bromelain

Effects

Anti-inflammatory: Reduces inflammation and modulates immune responses.

Mucolytic: Helps break down mucus, which can be beneficial for respiratory symptoms.

Relevant Conditions

LC & LPCVS: Helps manage inflammation and respiratory symptoms.

Viral Infections: May reduce inflammation and improve symptom management.

Sources

• Evidence-Based Complementary and Alternative Medicine
• Journal of Ethnopharmacology

Licorice

Effects

Antiviral and Anti-inflammatory: Contains glycyrrhizin, which has shown antiviral properties and can modulate inflammation.

Immune Support: Enhances immune function.

Relevant Conditions

LC & LPCVS: Reduces inflammation and supports immune function.

Viral Infections: Effective against herpesviruses, including EBV, HHV-6, and CMV.

Sources

• Phytotherapy Research
• Journal of Clinical Virology

Zinc

Effects

Immune Modulation: Essential for the function of various immune cells.

Antiviral: Inhibits viral replication and supports the immune response.

Relevant Conditions

LC & LPCVS: Supports immune function and may reduce viral reactivation.

Viral Infections: Shown to inhibit replication of several viruses, including those causing colds and herpesviruses.

Sources

• Frontiers in Immunology
• Journal of Nutrition

Piperine

Effects

Bioavailability Enhancer: Increases the absorption of other compounds, such as curcumin and quercetin.

Anti-inflammatory: Reduces inflammation and oxidative stress.

Relevant Conditions

LC & LPCVS: Enhances the effects of other supplements and reduces inflammation.

Viral Infections: Helps improve the efficacy of antiviral compounds.

Sources

• Journal of Ayurveda and Integrative Medicine
• Phytotherapy Research

Nattokinase

Effects

Fibrinolytic: Breaks down fibrin and helps prevent blood clots.

Anti-inflammatory: Reduces inflammation.

Relevant Conditions

LC & LPCVS: Helps manage blood clotting issues and inflammation.

Viral Infections: May support overall cardiovascular health and reduce inflammation.

Sources

• Journal of the American Nutraceutical Association
• Current Pharmaceutical Design